PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7682247-5 1993 The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin. Bleomycin 157-166 interleukin 6 Homo sapiens 23-26 7682247-2 1993 The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE). Bleomycin 89-98 interleukin 6 Homo sapiens 15-32 7682247-2 1993 The binding of heat shock factor (HSF) in response to heat and varying concentrations of bleomycin in the four cell lines was examined using a gel shift assay and a synthetic heat shock element (HSE). Bleomycin 89-98 interleukin 6 Homo sapiens 34-37 7682247-3 1993 Heat (45 degrees C, 10 min) and exposure to 1 micrograms/ml bleomycin for 1 h at 37 degrees C induced similar levels of HSF binding in all four cell lines. Bleomycin 60-69 interleukin 6 Homo sapiens 120-123 7682247-4 1993 We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding. Bleomycin 20-29 interleukin 6 Homo sapiens 113-116 7682247-4 1993 We also examined if bleomycin dose and the length of recovery from bleomycin treatment affected the induction of HSF binding. Bleomycin 67-76 interleukin 6 Homo sapiens 113-116 7682247-5 1993 The level of activated HSF binding to HSE was higher in cells treated with low doses (1 ng/ml) of bleomycin than in cells treated with 1 or 25 micrograms/ml bleomycin. Bleomycin 98-107 interleukin 6 Homo sapiens 23-26 7682247-6 1993 The amount of activated HSF was directly proportional to the time elapsed since bleomycin treatment. Bleomycin 80-89 interleukin 6 Homo sapiens 24-27 7682247-7 1993 Our results therefore indicate no difference between CHO and its bleomycin-sensitive derivatives in the ability to initiate the heat shock response as determined by the production of activated HSF in response to either heat or bleomycin. Bleomycin 227-236 interleukin 6 Homo sapiens 193-196