PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7629120-0 1995 c-Jun N-terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes. Cyclic AMP 81-85 mitogen-activated protein kinase 8 Homo sapiens 0-23 7629120-4 1995 Surprisingly, extracellular signal regulated kinase 2 (ERK1, ERK2, and ERK3) of MAP kinase were poorly inhibited by cAMP. Cyclic AMP 116-120 mitogen-activated protein kinase 1 Homo sapiens 14-53 7629120-4 1995 Surprisingly, extracellular signal regulated kinase 2 (ERK1, ERK2, and ERK3) of MAP kinase were poorly inhibited by cAMP. Cyclic AMP 116-120 mitogen-activated protein kinase 3 Homo sapiens 55-59 7629120-4 1995 Surprisingly, extracellular signal regulated kinase 2 (ERK1, ERK2, and ERK3) of MAP kinase were poorly inhibited by cAMP. Cyclic AMP 116-120 mitogen-activated protein kinase 12 Homo sapiens 71-75 7629120-5 1995 High concentration of cAMP also only weakly antagonized Raf-1 in T cells. Cyclic AMP 22-26 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 56-61 7629120-6 1995 The resistance of ERK and Raf-1 to cAMP clearly distinguishes T cells from fibroblasts. Cyclic AMP 35-39 mitogen-activated protein kinase 1 Homo sapiens 18-21 7629120-7 1995 In contrast, another MAP kinase homologue c-Jun N-terminal kinase (JNK) was inhibited by cAMP in good correlation with that of IL-2 suppression. Cyclic AMP 89-93 mitogen-activated protein kinase 8 Homo sapiens 42-65 7629120-7 1995 In contrast, another MAP kinase homologue c-Jun N-terminal kinase (JNK) was inhibited by cAMP in good correlation with that of IL-2 suppression. Cyclic AMP 89-93 mitogen-activated protein kinase 8 Homo sapiens 67-70 7629120-7 1995 In contrast, another MAP kinase homologue c-Jun N-terminal kinase (JNK) was inhibited by cAMP in good correlation with that of IL-2 suppression. Cyclic AMP 89-93 interleukin 2 Homo sapiens 127-131 7629120-8 1995 Moreover, JNK was antagonized by a delayed kinetics which is characteristic of cAMP inhibition. Cyclic AMP 79-83 mitogen-activated protein kinase 8 Homo sapiens 10-13 7629120-9 1995 Despite that both ERK and JNK are essential for T cell activation, selective inhibition by cAMP further supports the specific role of JNK in T cell activation. Cyclic AMP 91-95 mitogen-activated protein kinase 8 Homo sapiens 134-137