PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7595167-5 1995 In contrast, a single point mutation that results in the substitution of threonine for methionine within the catalytic core of the tyrosine kinase domain (codon 918, exon 16) is responsible for all 66 reported cases of MEN 2B. Threonine 73-82 ret proto-oncogene Homo sapiens 219-225