PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7564075-5 1995 After exposure to the lactate-PD containing 1.36% glucose, LDH activity was increased by more than 30%, proliferation of MC was inhibited by more than 30%, and IL-1 ra production was reduced significantly when compared to pyruvate-PD and the control solution. Glucose 50-57 interleukin 1 receptor antagonist Homo sapiens 160-167 7564075-6 1995 After preincubation with 3.86% glucose containing PD, all negative effects became even more pronounced in the lactate group whereas the MC maintained their integrity, rate of proliferation and IL-1 ra release after pre-exposure to pyruvate containing PD. Methylcholanthrene 136-138 interleukin 1 receptor antagonist Homo sapiens 193-200 7564075-7 1995 These results suggest that the acute toxic effects of commercially available PD on the integrity, proliferation and IL-1 ra production of MC can be avoided by the use of sodium pyruvate instead of sodium lactate. Methylcholanthrene 138-140 interleukin 1 receptor antagonist Homo sapiens 116-123 7564075-7 1995 These results suggest that the acute toxic effects of commercially available PD on the integrity, proliferation and IL-1 ra production of MC can be avoided by the use of sodium pyruvate instead of sodium lactate. SODIUM PYRUVATE 170-185 interleukin 1 receptor antagonist Homo sapiens 116-123