PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7561521-0	1995	Histamine enhances granulocyte-macrophage colony-stimulating factor and interleukin-6 production by human peripheral blood mononuclear cells.	Histamine	0-9	colony stimulating factor 2	Homo sapiens	19-67	
7561521-3	1995	Using ELISA and radioimmunoassay kits, histamine was found to enhance the production of GM-CSF (9.6-fold) and IL-6 (8.2-fold) by mononuclear cells but not by nonadherent cells or large granular lymphocytes.	Histamine	39-48	colony stimulating factor 2	Homo sapiens	88-94	
7561521-4	1995	Anti-GM-CSF and anti-IL-6 antibodies markedly blocked cytokine activity in CM-PBS, whereas the blocking effect in CM-histamine was moderate, indicating enhanced GM-CSF and IL-6 activity in CM-histamine.	Histamine	192-201	colony stimulating factor 2	Homo sapiens	161-167	
7561521-7	1995	We conclude that histamine is able to activate human mononuclear cells to generate cytokines such as GM-CSF and IL-6 via H1 and H2 receptors.	Histamine	17-26	colony stimulating factor 2	Homo sapiens	101-107