PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7559890-0 1995 Interleukin-1-mediated stimulation of prostaglandin E production is without effect on plasminogen activator activity in human granulosa lutein cell cultures. Prostaglandins E 38-53 interleukin 1 alpha Homo sapiens 0-13 7559890-5 1995 Exposure of GLCs to IL-1 resulted in a 50% increase in PGE production, a 33% suppression of PA activity, and a 75% increase in the ability of the corresponding conditioned media to inhibit exogenous urokinase activity. Prostaglandins E 55-58 interleukin 1 beta Homo sapiens 20-24 7559890-7 1995 Exposure of GLCs to IL-1 receptor antagonist abolished the ability of IL-1 to enhance PA inhibitory activity and PGE production, thereby establishing specific IL-1 receptor-mediated effects. Prostaglandins E 113-116 interleukin 1 receptor antagonist Homo sapiens 20-44 7559890-7 1995 Exposure of GLCs to IL-1 receptor antagonist abolished the ability of IL-1 to enhance PA inhibitory activity and PGE production, thereby establishing specific IL-1 receptor-mediated effects. Prostaglandins E 113-116 interleukin 1 beta Homo sapiens 20-24 7559890-7 1995 Exposure of GLCs to IL-1 receptor antagonist abolished the ability of IL-1 to enhance PA inhibitory activity and PGE production, thereby establishing specific IL-1 receptor-mediated effects. Prostaglandins E 113-116 interleukin 1 beta Homo sapiens 70-74 7559890-8 1995 The ability of IL-1 to suppress PA activity and to produce PAI-1 persisted in the presence of indomethacin, a potent inhibitor of PG synthesis. Indomethacin 94-106 interleukin 1 beta Homo sapiens 15-19 7559890-8 1995 The ability of IL-1 to suppress PA activity and to produce PAI-1 persisted in the presence of indomethacin, a potent inhibitor of PG synthesis. Indomethacin 94-106 serpin family E member 1 Homo sapiens 59-64 7559890-8 1995 The ability of IL-1 to suppress PA activity and to produce PAI-1 persisted in the presence of indomethacin, a potent inhibitor of PG synthesis. Prostaglandins 130-132 interleukin 1 beta Homo sapiens 15-19 7559890-8 1995 The ability of IL-1 to suppress PA activity and to produce PAI-1 persisted in the presence of indomethacin, a potent inhibitor of PG synthesis. Prostaglandins 130-132 serpin family E member 1 Homo sapiens 59-64 7559890-9 1995 Likewise, transforming growth factor-beta 1 suppressed the ability of IL-1 to stimulate PGE production without affecting the IL-1-induced effects on the PA system. Prostaglandins E 88-91 transforming growth factor beta 1 Homo sapiens 10-43 7559890-9 1995 Likewise, transforming growth factor-beta 1 suppressed the ability of IL-1 to stimulate PGE production without affecting the IL-1-induced effects on the PA system. Prostaglandins E 88-91 interleukin 1 beta Homo sapiens 70-74 7559890-10 1995 The present findings suggest a pluripotent response of GLCs to IL-1, characterized by the induction of PAI-1 and the suppression of PA occurring concurrent with, but independent of, PG production. Prostaglandins 182-184 interleukin 1 beta Homo sapiens 63-67