PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7505123-1	1993	The beta-glucan receptor, found on monocytes and neutrophils, binds glucose polymers derived from fungi.	Glucose	68-75	C-type lectin domain containing 7A	Homo sapiens	4-24	
7505123-3	1993	We have investigated the effect of beta-glucans on the production of interleukin-1 (IL-1) and its naturally occurring inhibitor, the IL-1 receptor antagonist (IL-1Ra).	beta-Glucans	35-47	interleukin 1 alpha	Homo sapiens	69-82	
7505123-3	1993	We have investigated the effect of beta-glucans on the production of interleukin-1 (IL-1) and its naturally occurring inhibitor, the IL-1 receptor antagonist (IL-1Ra).	beta-Glucans	35-47	interleukin 1 alpha	Homo sapiens	84-88	
7505123-4	1993	Particulate beta-glucan induced IL-1Ra production from human peripheral blood mononuclear cells (PBMC) but did not stimulate IL-1 beta synthesis or gene expression in these same cells.	beta-Glucans	12-23	interleukin 1 receptor antagonist	Homo sapiens	32-38	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	PBMC	32-36	interleukin 1 receptor antagonist	Homo sapiens	132-138	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	beta-Glucans	48-59	interleukin 1 receptor antagonist	Homo sapiens	132-138	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	beta-Glucans	48-59	interleukin 1 receptor antagonist	Homo sapiens	230-236	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	beta-Glucans	107-118	interleukin 1 receptor antagonist	Homo sapiens	132-138	
7505123-7	1993	In support of this, monomeric beta-glucan immobilized on plastic surfaces stimulated IL-1Ra production.	beta-Glucans	30-41	interleukin 1 receptor antagonist	Homo sapiens	85-91	
7505123-8	1993	Vitamin D3, which increases the functional capacity of beta-glucan receptors, increased IL-1Ra production induced by particulate beta-glucan, whereas dexamethasone suppressed IL-1Ra synthesis.	Cholecalciferol	0-10	interleukin 1 receptor antagonist	Homo sapiens	88-94	
7505123-8	1993	Vitamin D3, which increases the functional capacity of beta-glucan receptors, increased IL-1Ra production induced by particulate beta-glucan, whereas dexamethasone suppressed IL-1Ra synthesis.	beta-Glucans	55-66	interleukin 1 receptor antagonist	Homo sapiens	88-94	
7505123-8	1993	Vitamin D3, which increases the functional capacity of beta-glucan receptors, increased IL-1Ra production induced by particulate beta-glucan, whereas dexamethasone suppressed IL-1Ra synthesis.	Dexamethasone	150-163	interleukin 1 receptor antagonist	Homo sapiens	175-181	
7505123-9	1993	Because of their differential effects on cytokine production, beta-glucans may be used to therapeutic advantage in the diseases in which IL-1 is implicated.	beta-Glucans	62-74	interleukin 1 alpha	Homo sapiens	137-141