PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7478553-1	1995	Formation of a complex of the nucleotide exchange factor Sos, the SH2 and SH3 containing adaptor protein Grb2/Sem-5 and tyrosine phosphorylated EGF receptor and Shc has been implicated in the activation of Ras by epidermal growth factor (EGF) in fibroblasts: related mechanisms for activation of Ras operate in other cell types.	Tyrosine	120-128	growth factor receptor bound protein 2	Homo sapiens	105-109	
7478553-1	1995	Formation of a complex of the nucleotide exchange factor Sos, the SH2 and SH3 containing adaptor protein Grb2/Sem-5 and tyrosine phosphorylated EGF receptor and Shc has been implicated in the activation of Ras by epidermal growth factor (EGF) in fibroblasts: related mechanisms for activation of Ras operate in other cell types.	Tyrosine	120-128	SHC adaptor protein 1	Homo sapiens	161-164	
7478553-4	1995	This modification of Sos does not alter its ability to bind Grb2, but correlates with strong inhibition of the binding of the Sos/Grb2 complex to tyrosine phosphorylated sequences, either a tyrosine phosphopeptide in cell lysates or p36 in intact cells.	Tyrosine	146-154	growth factor receptor bound protein 2	Homo sapiens	130-134	
7478553-4	1995	This modification of Sos does not alter its ability to bind Grb2, but correlates with strong inhibition of the binding of the Sos/Grb2 complex to tyrosine phosphorylated sequences, either a tyrosine phosphopeptide in cell lysates or p36 in intact cells.	Tyrosine	146-154	5'-nucleotidase, cytosolic IIIA	Homo sapiens	233-236	
7478553-4	1995	This modification of Sos does not alter its ability to bind Grb2, but correlates with strong inhibition of the binding of the Sos/Grb2 complex to tyrosine phosphorylated sequences, either a tyrosine phosphopeptide in cell lysates or p36 in intact cells.	Tyrosine	190-198	growth factor receptor bound protein 2	Homo sapiens	130-134	
7478553-5	1995	This effect, along with the mobility shift of Sos, can be mimicked in vitro by phosphorylation of Sos by the mitogen-activated protein kinase, ERK1.	sulfur monoxide	46-49	mitogen-activated protein kinase 3	Homo sapiens	143-147	
7478553-5	1995	This effect, along with the mobility shift of Sos, can be mimicked in vitro by phosphorylation of Sos by the mitogen-activated protein kinase, ERK1.	sulfur monoxide	98-101	mitogen-activated protein kinase 3	Homo sapiens	143-147	
7478553-6	1995	A novel negative feedback mechanism therefore exists whereby activation of MAP kinases through Ras results in the uncoupling of the Sos/Grb2 complex from tyrosine kinase substrates without blocking the interaction of Sos with Grb2.	sulfur monoxide	132-135	growth factor receptor bound protein 2	Homo sapiens	136-140