PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 4799079-2 1973 Drugs such as phenobarbitone and phenylbutazone, which increase the concentration of microsomal haem and cytochrome P-450, also increase the saturation of rat liver apo-(tryptophan pyrrolase) with its haem activator, as does the haem precursor 5-aminolaevulinate. Phenobarbital 14-28 tryptophan 2,3-dioxygenase Rattus norvegicus 170-190