PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35584723-3 2022 In this study, our objective is to study ethanol-induced activation of TGF-beta1 and associated mechanisms of neuroinflammation and apoptosis. Ethanol 41-48 transforming growth factor, beta 1 Mus musculus 71-80 35584723-5 2022 Our study demonstrated that the activation of TGF-beta1 in ethanol ingestion correlated with the induction of free radical generating enzyme NADPH oxidase (NOX). Ethanol 59-66 transforming growth factor, beta 1 Mus musculus 46-55 35584723-6 2022 Further, using TGF-beta type I receptor (TGF-betaRI) inhibitor SB431542 and TGF-beta antagonist Smad7, we established that the alcohol-induced activation of TGF-beta1 impairs antioxidant signaling pathways and leads to neuroinflammation and apoptosis. 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide 63-71 transforming growth factor, beta 1 Mus musculus 157-166 35584723-6 2022 Further, using TGF-beta type I receptor (TGF-betaRI) inhibitor SB431542 and TGF-beta antagonist Smad7, we established that the alcohol-induced activation of TGF-beta1 impairs antioxidant signaling pathways and leads to neuroinflammation and apoptosis. Alcohols 127-134 transforming growth factor alpha Mus musculus 76-84 35584723-6 2022 Further, using TGF-beta type I receptor (TGF-betaRI) inhibitor SB431542 and TGF-beta antagonist Smad7, we established that the alcohol-induced activation of TGF-beta1 impairs antioxidant signaling pathways and leads to neuroinflammation and apoptosis. Alcohols 127-134 SMAD family member 7 Mus musculus 96-101 35584723-6 2022 Further, using TGF-beta type I receptor (TGF-betaRI) inhibitor SB431542 and TGF-beta antagonist Smad7, we established that the alcohol-induced activation of TGF-beta1 impairs antioxidant signaling pathways and leads to neuroinflammation and apoptosis. Alcohols 127-134 transforming growth factor, beta 1 Mus musculus 157-166