PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35503561-5 2022 Specifically, SARS-CoV-2 spike protein-induced MC degranulation resulted in alveolar-capillary injury, while pretreatment of pulmonary microvascular endothelial cells with antihistamines prevented adhesion junction disruption; predictably, the combination of antiviral drug remdesivir with the antihistamine loratadine, a histamine receptor 1 (HR1) antagonist, dampened viral replication and inflammation, thereby greatly reducing lung injury. remdesivir 274-284 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 25-30