PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35310033-5 2022 In this review, a systematic survey was executed to collect the literature on alkaloids and their health complications, from which we found that majority of alkaloids exhibit anti-inflammatory action via nuclear factor-kappaB and cyclooxygenase-2 (COX-2), and neuroprotective interaction through acetylcholinesterase (AChE), COX, and beta-site amyloid precursor protein activity. Alkaloids 78-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 296-316 35310033-5 2022 In this review, a systematic survey was executed to collect the literature on alkaloids and their health complications, from which we found that majority of alkaloids exhibit anti-inflammatory action via nuclear factor-kappaB and cyclooxygenase-2 (COX-2), and neuroprotective interaction through acetylcholinesterase (AChE), COX, and beta-site amyloid precursor protein activity. Alkaloids 78-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 318-322 35310033-5 2022 In this review, a systematic survey was executed to collect the literature on alkaloids and their health complications, from which we found that majority of alkaloids exhibit anti-inflammatory action via nuclear factor-kappaB and cyclooxygenase-2 (COX-2), and neuroprotective interaction through acetylcholinesterase (AChE), COX, and beta-site amyloid precursor protein activity. Alkaloids 157-166 acetylcholinesterase (Cartwright blood group) Homo sapiens 296-316 35310033-5 2022 In this review, a systematic survey was executed to collect the literature on alkaloids and their health complications, from which we found that majority of alkaloids exhibit anti-inflammatory action via nuclear factor-kappaB and cyclooxygenase-2 (COX-2), and neuroprotective interaction through acetylcholinesterase (AChE), COX, and beta-site amyloid precursor protein activity. Alkaloids 157-166 acetylcholinesterase (Cartwright blood group) Homo sapiens 318-322