PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35127652-0	2021	Synthesis of New 3-Arylcoumarins Bearing N-Benzyl Triazole Moiety: Dual Lipoxygenase and Butyrylcholinesterase Inhibitors With Anti-Amyloid Aggregation and Neuroprotective Properties Against Alzheimer"s Disease.	3-arylcoumarins	17-32	butyrylcholinesterase	Rattus norvegicus	89-110	
35127652-1	2021	A novel series of coumarin derivatives linked to the N-benzyl triazole group were synthesized and evaluated against 15-lipoxygenase (15-LOX), and acetyl- and butyrylcholinesterase (AChE and BuChE) to find the most potent derivative against Alzheimer"s disease (AD).	coumarin	18-26	arachidonate 15-lipoxygenase	Rattus norvegicus	116-131	
35127652-1	2021	A novel series of coumarin derivatives linked to the N-benzyl triazole group were synthesized and evaluated against 15-lipoxygenase (15-LOX), and acetyl- and butyrylcholinesterase (AChE and BuChE) to find the most potent derivative against Alzheimer"s disease (AD).	coumarin	18-26	arachidonate 15-lipoxygenase	Rattus norvegicus	133-139	
35127652-1	2021	A novel series of coumarin derivatives linked to the N-benzyl triazole group were synthesized and evaluated against 15-lipoxygenase (15-LOX), and acetyl- and butyrylcholinesterase (AChE and BuChE) to find the most potent derivative against Alzheimer"s disease (AD).	coumarin	18-26	acetylcholinesterase	Rattus norvegicus	181-185	
35127652-3	2021	Among the most active BuChE and 15-LOX inhibitors, 8l and 8n exhibited an excellent neuroprotective effect, higher than the standard drug (quercetin) on the PC12 cell model injured by H2O2 and significantly reduced aggregation of amyloid Abeta1-42, with potencies of 1.44 and 1.79 times higher than donepezil, respectively.	8l	51-53	arachidonate 15-lipoxygenase	Rattus norvegicus	32-38