PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34973332-2 2022 Humans express two isoforms of HO: the inducible HO-1, which is up-regulated in response to various stressors, including excess heme, and the constitutive HO-2. Heme 128-132 heme oxygenase 1 Homo sapiens 49-53 34973332-8 2022 When heme is in excess, HO-1 is induced and both HO-2 and HO-1 can provide protection from heme toxicity via enzymatic degradation. Heme 5-9 heme oxygenase 1 Homo sapiens 24-28 34973332-8 2022 When heme is in excess, HO-1 is induced and both HO-2 and HO-1 can provide protection from heme toxicity via enzymatic degradation. Heme 5-9 heme oxygenase 1 Homo sapiens 58-62 34973332-8 2022 When heme is in excess, HO-1 is induced and both HO-2 and HO-1 can provide protection from heme toxicity via enzymatic degradation. Heme 91-95 heme oxygenase 1 Homo sapiens 58-62