PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34787621-0 2021 Potential interference of graphene nanosheets in immune response via disrupting the recognition of HLA-presented KK10 by TCR: a molecular dynamics simulation study. Graphite 26-34 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 121-124 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 112-127 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 129-132 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 252-255 34787621-4 2021 For the illustrated human immunodeficiency virus (HIV) antigen peptide KK10, human leukocyte antigen (HLA), and T cell receptor (TCR) ternary complex, we found that the graphene nanosheet could disrupt the critical protein-protein interactions between TCR and peptide-HLA and impair the antigen recognition by TCR, leaving the antigen presentation unaffected. Graphite 169-177 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 310-313 34787621-5 2021 Moreover, the hydrophobic interaction and van der Waals potential energy collectively drive the spontaneous separation of TCR from the peptide-HLA complex by graphene nanosheets. Graphite 158-166 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 122-125