PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34725737-0	2021	How does nintedanib overcome cancer drug-resistant mutation of RET protein-tyrosine kinase: insights from molecular dynamics simulations.	nintedanib	9-19	ret proto-oncogene	Homo sapiens	63-66	
34725737-5	2021	Nintedanib can effectively inhibit the RET L881V mutant, whereas its analog compound 1 is unable to combat this mutant.	nintedanib	0-10	ret proto-oncogene	Homo sapiens	39-42	
34725737-7	2021	Here, molecular dynamics (MD) simulations, binding free energy calculations, and structural analysis were performed to uncover the mechanism of overcoming the resistance of RET L881V mutant to nintedanib.	nintedanib	193-203	ret proto-oncogene	Homo sapiens	173-176