PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34714861-10	2021	A significant difference in enzyme activity of the catalytic site mutants was observed as compared to the wildtype, and subsequent AChE activity showed that esterase activity of PON2 is responsible for the hydrolysis of DHC and PB.	Donepezil	220-223	acetylcholinesterase (Cartwright blood group)	Homo sapiens	131-135	
34714861-10	2021	A significant difference in enzyme activity of the catalytic site mutants was observed as compared to the wildtype, and subsequent AChE activity showed that esterase activity of PON2 is responsible for the hydrolysis of DHC and PB.	Donepezil	220-223	paraoxonase 2	Homo sapiens	178-182	
34714861-10	2021	A significant difference in enzyme activity of the catalytic site mutants was observed as compared to the wildtype, and subsequent AChE activity showed that esterase activity of PON2 is responsible for the hydrolysis of DHC and PB.	Pyridostigmine Bromide	228-230	acetylcholinesterase (Cartwright blood group)	Homo sapiens	131-135	
34714861-10	2021	A significant difference in enzyme activity of the catalytic site mutants was observed as compared to the wildtype, and subsequent AChE activity showed that esterase activity of PON2 is responsible for the hydrolysis of DHC and PB.	Pyridostigmine Bromide	228-230	paraoxonase 2	Homo sapiens	178-182	
34714861-12	2021	Thus, our data suggested that the esterase activity of PON2 was mainly responsible for the hydrolysis of AChEI, DHC, and PB, and that might be responsible for the variation in individual response to AChEI therapy.	Donepezil	112-115	paraoxonase 2	Homo sapiens	55-59	
34714861-12	2021	Thus, our data suggested that the esterase activity of PON2 was mainly responsible for the hydrolysis of AChEI, DHC, and PB, and that might be responsible for the variation in individual response to AChEI therapy.	Pyridostigmine Bromide	121-123	paraoxonase 2	Homo sapiens	55-59