PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34537235-2 2021 The principal step in this critical cellular process is the hydroxylation of either or both of the two conserved proline residues P402 and P564 within the oxygen-dependent degradation domain (ODD) of HIF-1alpha subunit via prolyl hydroxylases, which is necessary for binding VHL. Proline 113-120 von Hippel-Lindau tumor suppressor Homo sapiens 275-278