PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34411897-4	2021	To date, AC6, a calcium-inhibited AC, is the primary isoform studied in bone.	Calcium	16-23	adenylate cyclase 6	Mus musculus	9-12	
34411897-6	2021	Using a transcriptomic dataset of MLO-Y4 osteocyte-like cells from the NIH Gene Expression Omnibus, we identified AC3 as the only calcium-stimulated isoform expressed.	Calcium	130-137	adenylate cyclase 3	Mus musculus	114-117	
34411897-7	2021	We show that inhibiting AC3 in MLO-Y4 cells results in decreased cAMP-signaling with fluid shear and increased osteogenic response to fluid flow (measured as Ptgs2 expression) of longer durations, but not shorter.	Cyclic AMP	65-69	adenylate cyclase 3	Mus musculus	24-27	
34411897-10	2021	Regulation of GSK3beta is downstream of the primary cilium and cAMP signaling, and with western blots we found that GSK3beta inhibition by phosphorylation is increased after fluid shear in AC3 knockdown groups.	Cyclic AMP	63-67	glycogen synthase kinase 3 alpha	Mus musculus	14-22	
34411897-10	2021	Regulation of GSK3beta is downstream of the primary cilium and cAMP signaling, and with western blots we found that GSK3beta inhibition by phosphorylation is increased after fluid shear in AC3 knockdown groups.	Cyclic AMP	63-67	glycogen synthase kinase 3 alpha	Mus musculus	116-124