PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34303883-8	2021	In MCF7 cells, letrozole caused a dose dependent increase in FADS2-catalyzed DGLA synthesis, which plateaued in SK-N-SH cells.	8,11,14-Eicosatrienoic Acid	77-81	fatty acid desaturase 2	Homo sapiens	61-66	
34303883-9	2021	CONCLUSION: Letrozole restores Delta6-desaturase mediated synthesis of the anti-inflammatory PGE1-precursor DGLA in vitro and is the first endocrine-active agent to have opposing effects on FADS1 and FADS2 catalyzed activities.	8,11,14-Eicosatrienoic Acid	108-112	fatty acid desaturase 2	Homo sapiens	37-48