PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34261004-5 2021 From a list of differential expressed genes, cisplatin downregulated the cyclin-dependent kinase inhibitor 1 (CDKN1A), tumor necrosis factor (FAS), and sestrin-1 (SESN1) genes responsible for modifying signaling pathways, including the p53, JAK-STAT, FOXO, MAPK, mTOR, P13-AKT, Toll-like receptor (TLR), adipocytokine, and insulin signaling pathways. Cisplatin 45-54 tumor protein p53 Homo sapiens 236-239