PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34198827-0 2021 Carnosic Acid Attenuates an Early Increase in ROS Levels during Adipocyte Differentiation by Suppressing Translation of Nox4 and Inducing Translation of Antioxidant Enzymes. salvin 0-13 NADPH oxidase 4 Homo sapiens 120-124 34198827-0 2021 Carnosic Acid Attenuates an Early Increase in ROS Levels during Adipocyte Differentiation by Suppressing Translation of Nox4 and Inducing Translation of Antioxidant Enzymes. Reactive Oxygen Species 46-49 NADPH oxidase 4 Homo sapiens 120-124 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 NADPH oxidase 4 Homo sapiens 107-111 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 neutrophil cytosolic factor 1 Homo sapiens 114-121 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 cytochrome b-245 alpha chain Homo sapiens 127-134 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 nuclear factor kappa B subunit 1 Homo sapiens 163-185 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 nuclear factor kappa B subunit 1 Homo sapiens 187-196 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 nuclear factor kappa B subunit 1 Homo sapiens 202-211 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). salvin 0-13 NFKB inhibitor alpha Homo sapiens 223-227 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). NADP 44-49 NADPH oxidase 4 Homo sapiens 107-111 34198827-5 2021 Carnosic acid attenuates the translation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 4 (Nox4), p47phox, and p22phox, and the phosphorylation of nuclear factor-kappa B (NF-kappaB) and NF-kappaB inhibitor (IkBa). NADP 51-94 NADPH oxidase 4 Homo sapiens 107-111 34198827-6 2021 The translocation of NF-kappaB into the nucleus was also decreased by carnosic acid. salvin 70-83 nuclear factor kappa B subunit 1 Homo sapiens 21-30 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 heme oxygenase 1 Homo sapiens 56-72 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 heme oxygenase 1 Homo sapiens 74-78 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 glutamate-cysteine ligase catalytic subunit Homo sapiens 81-114 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 glutathione S-transferase kappa 1 Homo sapiens 133-158 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 glutathione S-transferase kappa 1 Homo sapiens 160-163 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 NFE2 like bZIP transcription factor 2 Homo sapiens 219-262 34198827-7 2021 In addition, carnosic acid increased the translation of heme oxygenase-1 (HO-1), gamma-glutamylcysteine synthetase (gamma-GCSc), and glutathione S-transferase (GST) and both the translation and nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2). salvin 13-26 NFE2 like bZIP transcription factor 2 Homo sapiens 264-268 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. salvin 44-57 nuclear factor kappa B subunit 1 Homo sapiens 200-209 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. salvin 44-57 NADPH oxidase 4 Homo sapiens 234-238 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. salvin 44-57 NFE2 like bZIP transcription factor 2 Homo sapiens 301-305 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. salvin 44-57 heme oxygenase 1 Homo sapiens 367-371 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. salvin 44-57 glutathione S-transferase kappa 1 Homo sapiens 388-391 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 78-81 nuclear factor kappa B subunit 1 Homo sapiens 200-209 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 78-81 NADPH oxidase 4 Homo sapiens 234-238 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 78-81 NFE2 like bZIP transcription factor 2 Homo sapiens 301-305 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 78-81 heme oxygenase 1 Homo sapiens 367-371 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 78-81 glutathione S-transferase kappa 1 Homo sapiens 388-391 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 162-165 NADPH oxidase 4 Homo sapiens 234-238 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 261-264 NFE2 like bZIP transcription factor 2 Homo sapiens 301-305