PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34165168-0	2021	MicroRNA-10b modulates cisplatin tolerance by targeting p53 directly in lung cancer cells.	Cisplatin	23-32	tumor protein p53	Homo sapiens	56-59	
34165168-6	2021	In functional assays, upregulation of the p53 signaling pathway following cisplatin treatment was associated with decreased levels of miR-10b and upregulation of the luciferase activity of wild-type, but not 1,584, 2,032-dual-mutant, p53 3"-UTR.	Cisplatin	74-83	tumor protein p53	Homo sapiens	42-45	
34165168-7	2021	The ectopic expression of miR-10b-agomir attenuated the stability of p53 3"-UTR and the expression of p53 and its downstream effectors induced by cisplatin.	Cisplatin	146-155	tumor protein p53	Homo sapiens	69-72	
34165168-7	2021	The ectopic expression of miR-10b-agomir attenuated the stability of p53 3"-UTR and the expression of p53 and its downstream effectors induced by cisplatin.	Cisplatin	146-155	tumor protein p53	Homo sapiens	102-105	
34165168-8	2021	By contrast, the knockdown of miR-10b induced the stability of p53 3"-UTR and increased levels of p53 and the sensitivity of A549 cells to cisplatin treatment.	Cisplatin	139-148	tumor protein p53	Homo sapiens	63-66	
34165168-8	2021	By contrast, the knockdown of miR-10b induced the stability of p53 3"-UTR and increased levels of p53 and the sensitivity of A549 cells to cisplatin treatment.	Cisplatin	139-148	tumor protein p53	Homo sapiens	98-101	
34165168-12	2021	These findings indicate a novel pathway in which cisplatin induces the levels of p53 by increasing mRNA stability via miR-10b, indicating a novel oncogenic role of miR-10b in promoting the malignant characteristics of non-small cell lung carcinoma.	Cisplatin	49-58	tumor protein p53	Homo sapiens	81-84