PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34078833-0 2021 Remifentanil protects against myocardial ischemia/reperfusion injury via miR-205-mediated regulation of PINK1. Remifentanil 0-12 microRNA 205 Rattus norvegicus 73-80 34078833-8 2021 However, preconditioning with remifentanil reduced miR-205 and enhanced PINK1. Remifentanil 30-42 microRNA 205 Rattus norvegicus 51-58 34078833-9 2021 Moreover, over-expression of miR-205 decreased PINK1 expression and counteracted the effects of remifentanil-induced increase of cell viability and decrease of cell apoptosis in hypoxia/reoxygenation-induced cardiomyocytes. Remifentanil 96-108 microRNA 205 Rattus norvegicus 29-36 34078833-10 2021 Injection with miR-205 antagomir improved remifentanil-induced decrease of infarct size and LDH (lactic acid dehydrogenase) activity in rat model with I/R injury. Remifentanil 42-54 microRNA 205 Rattus norvegicus 15-22 34078833-11 2021 In conclusion, miR-205 might participate in the protective effect of remifentanil in rat myocardial I/R injury via regulation of PINK1, providing a potential target for amelioration of cardiovascular ischemic disease. Remifentanil 69-81 microRNA 205 Rattus norvegicus 15-22