PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33976430-4 2021 Here we show that retinoic acid-inducible gene-I (RIG-I) sufficiently restrains SARS-CoV-2 replication in human lung cells in a type I/III interferon (IFN)-independent manner. Tretinoin 18-31 DExD/H-box helicase 58 Homo sapiens 50-55 33976430-9 2021 By contrast, the anti-SARS-CoV-2 activity was restored by all-trans retinoic acid treatment through upregulation of RIG-I protein expression in primary lung cells derived from patients with chronic obstructive pulmonary disease. Tretinoin 68-81 DExD/H-box helicase 58 Homo sapiens 116-121