PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33972436-6 2021 Utilizing loss- and gain-of-function approaches in cultured epithelia and murine colonoids, we demonstrate that EA elicits prominent CREB phosphorylation through cyclic AMP-independent mechanisms that requires elements of the mitogen-activated protein kinase signaling pathway. Cyclic AMP 162-172 cAMP responsive element binding protein 1 Mus musculus 133-137