PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33822049-2	2021	SUMMARY ANSWER: Podocalyxin (PCX), a transmembrane protein, was identified as a key negative regulator of endometrial epithelial receptivity; specific downregulation of PCX in the luminal epithelium in the mid-secretory phase, likely mediated by progesterone, may act as a critical step in converting endometrial surface from a non-receptive to an implantation-permitting state.	Progesterone	246-258	podocalyxin like	Homo sapiens	16-27	
33822049-2	2021	SUMMARY ANSWER: Podocalyxin (PCX), a transmembrane protein, was identified as a key negative regulator of endometrial epithelial receptivity; specific downregulation of PCX in the luminal epithelium in the mid-secretory phase, likely mediated by progesterone, may act as a critical step in converting endometrial surface from a non-receptive to an implantation-permitting state.	Progesterone	246-258	podocalyxin like	Homo sapiens	29-32	
33822049-2	2021	SUMMARY ANSWER: Podocalyxin (PCX), a transmembrane protein, was identified as a key negative regulator of endometrial epithelial receptivity; specific downregulation of PCX in the luminal epithelium in the mid-secretory phase, likely mediated by progesterone, may act as a critical step in converting endometrial surface from a non-receptive to an implantation-permitting state.	Progesterone	246-258	podocalyxin like	Homo sapiens	169-172	
33822049-10	2021	To investigate whether PCX is regulated by progesterone, the master driver of endometrial differentiation, primary HEECs were treated in culture with estradiol and progesterone and analyzed by RT-PCR (n = 5) and western blot (n = 4).	Progesterone	43-55	podocalyxin like	Homo sapiens	23-26	
33822049-14	2021	Progesterone was confirmed to be able to suppress PCX in primary HEECs, suggesting this hormone likely mediates the downregulation of luminal PCX in vivo for receptivity.	Progesterone	0-12	podocalyxin like	Homo sapiens	50-53	
33822049-14	2021	Progesterone was confirmed to be able to suppress PCX in primary HEECs, suggesting this hormone likely mediates the downregulation of luminal PCX in vivo for receptivity.	Progesterone	0-12	podocalyxin like	Homo sapiens	142-145	
33822049-17	2021	Future study would need to investigate how progesterone differentially regulates PCX in endometrial epithelial subtypes.	Progesterone	43-55	podocalyxin like	Homo sapiens	81-84	
33822049-21	2021	The study also discovered PCX as progesterone target in HEECs, identifying a potentially useful functional biomarker to monitor progesterone action, such as in the optimization of progesterone type/dose/route of administration for luteal support.	Progesterone	33-45	podocalyxin like	Homo sapiens	26-29	
33822049-21	2021	The study also discovered PCX as progesterone target in HEECs, identifying a potentially useful functional biomarker to monitor progesterone action, such as in the optimization of progesterone type/dose/route of administration for luteal support.	Progesterone	128-140	podocalyxin like	Homo sapiens	26-29	
33822049-21	2021	The study also discovered PCX as progesterone target in HEECs, identifying a potentially useful functional biomarker to monitor progesterone action, such as in the optimization of progesterone type/dose/route of administration for luteal support.	Progesterone	128-140	podocalyxin like	Homo sapiens	26-29