PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33674449-6 2021 Conversely, deletion of the C-terminal TTK-LKS motif in DNAJB6 and DNAJB8, a region not required to suppress polyQ aggregation, abolished its ability to inhibit inclusion formation by FlucDM Thus, our data suggest that DNAJB6 and DNAJB8 possess two distinct regions for binding substrates, one that is responsible for binding beta-hairpins that form during amyloid formation and another that interacts with exposed hydrophobic patches in aggregation-prone clients. polyglutamine 109-114 DnaJ heat shock protein family (Hsp40) member B6 Homo sapiens 56-62