PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33656855-4 2021 Here we show that MAT2A has a sequential mechanism with a rate-limiting step of formation of AdoMet, followed by rapid hydrolysis of the beta-gamma bond of triphosphate, and rapid release of phosphate and pyrophosphate. diphosphoric acid 205-218 methionine adenosyltransferase 2A Homo sapiens 18-23