PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33576879-0 2021 Niacin stimulates EPH4EV mammary epithelial cell proliferation and mammary gland development in pubertal mice through activation of AKT/mTOR and ERK1/2 signaling pathways. Niacin 0-6 thymoma viral proto-oncogene 1 Mus musculus 132-135 33576879-4 2021 The results showed that niacin could activate the AKT/mTOR and ERK signaling pathways and increase phosphorylation of 4EBP1 to promote the synthesis of cell proliferation markers, leading to the dissociation of the Rb-E2F1 complex in mMECs. Niacin 24-30 thymoma viral proto-oncogene 1 Mus musculus 50-53 33576879-5 2021 In addition, 0.5% niacin promoted mammary duct development, increased the expression of cyclin D1/D3 and PCNA and activated Akt/mTOR and ERK1/2 in the mammary glands of pubertal mice. Niacin 18-24 thymoma viral proto-oncogene 1 Mus musculus 124-127 33576879-6 2021 These results strongly suggest that niacin stimulates mammary gland development in pubertal mice through the Akt/mTOR and ERK1/2 signaling pathways. Niacin 36-42 thymoma viral proto-oncogene 1 Mus musculus 109-112