PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33490645-0 2021 Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells. Ellagic Acid 0-12 cytochrome b-245 beta chain Homo sapiens 85-94 33490645-0 2021 Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells. 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 45-56 cytochrome b-245 beta chain Homo sapiens 85-94 33490645-5 2021 Semiquantitative RT-PCR showed that transcription level of gp91-phox was certainly decreased (to ~70%) in ATRA plus ellagic acid-treated cells, while that of gp91-phox was significantly increased (to ~160%) in ATRA plus urolithin A-treated cells. Tretinoin 106-110 cytochrome b-245 beta chain Homo sapiens 59-68 33490645-5 2021 Semiquantitative RT-PCR showed that transcription level of gp91-phox was certainly decreased (to ~70%) in ATRA plus ellagic acid-treated cells, while that of gp91-phox was significantly increased (to ~160%) in ATRA plus urolithin A-treated cells. Ellagic Acid 116-128 cytochrome b-245 beta chain Homo sapiens 59-68 33490645-5 2021 Semiquantitative RT-PCR showed that transcription level of gp91-phox was certainly decreased (to ~70%) in ATRA plus ellagic acid-treated cells, while that of gp91-phox was significantly increased (to ~160%) in ATRA plus urolithin A-treated cells. Ellagic Acid 116-128 cytochrome b-245 beta chain Homo sapiens 158-167 33490645-5 2021 Semiquantitative RT-PCR showed that transcription level of gp91-phox was certainly decreased (to ~70%) in ATRA plus ellagic acid-treated cells, while that of gp91-phox was significantly increased (to ~160%) in ATRA plus urolithin A-treated cells. Tretinoin 210-214 cytochrome b-245 beta chain Homo sapiens 59-68 33490645-5 2021 Semiquantitative RT-PCR showed that transcription level of gp91-phox was certainly decreased (to ~70%) in ATRA plus ellagic acid-treated cells, while that of gp91-phox was significantly increased (to ~160%) in ATRA plus urolithin A-treated cells. 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 220-231 cytochrome b-245 beta chain Homo sapiens 59-68 33490645-6 2021 Chromatin immunoprecipitation assay suggested that urolithin A enhanced acetylations of Lys-9 residues of histone H3 within chromatin surrounding the promoter region of gp91-phox gene, but ellagic acid suppressed the acetylations. 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 51-62 cytochrome b-245 beta chain Homo sapiens 169-178 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). Tretinoin 34-38 cytochrome b-245 alpha chain Homo sapiens 97-105 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). Tretinoin 34-38 cytochrome b-245 beta chain Homo sapiens 121-130 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). Tretinoin 34-38 cytochrome b-245 alpha chain Homo sapiens 217-225 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). Tretinoin 34-38 cytochrome b-245 beta chain Homo sapiens 240-249 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 44-55 cytochrome b-245 alpha chain Homo sapiens 97-105 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 44-55 cytochrome b-245 beta chain Homo sapiens 121-130 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 44-55 cytochrome b-245 alpha chain Homo sapiens 217-225 33490645-7 2021 Immunoblotting also revealed that ATRA plus urolithin A-treatment up-regulated protein levels of p22-phox (to ~160%) and gp91-phox (to ~170%) although ATRA plus ellagic acid-treatment down-regulated protein levels of p22-phox (to ~70%) and gp91-phox (to ~60%). 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 44-55 cytochrome b-245 beta chain Homo sapiens 240-249 33490645-8 2021 These results suggested that conversion of ellagic acid to urolithin A in gut may bring about reverse effects on the gp91-phox gene expression, resulting in opposite alterations in O2 --generating activity of intestinal macrophages. Ellagic Acid 43-55 cytochrome b-245 beta chain Homo sapiens 117-126 33490645-8 2021 These results suggested that conversion of ellagic acid to urolithin A in gut may bring about reverse effects on the gp91-phox gene expression, resulting in opposite alterations in O2 --generating activity of intestinal macrophages. 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one 59-70 cytochrome b-245 beta chain Homo sapiens 117-126