PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33450182-4 2021 However, the drug inhibition mechanism remains unclear because of the scarce structural information regarding the drug- and potassium-bound hERG channels. Potassium 124-133 ETS transcription factor ERG Homo sapiens 140-144 33450182-5 2021 In this study, we obtained the cryo-EM density map of potassium-bound hERG channel complexed with astemizole, a well-known hERG inhibitor that increases risk of potentially fatal arrhythmia, at 3.5-A resolution. Potassium 54-63 ETS transcription factor ERG Homo sapiens 70-74 33450182-5 2021 In this study, we obtained the cryo-EM density map of potassium-bound hERG channel complexed with astemizole, a well-known hERG inhibitor that increases risk of potentially fatal arrhythmia, at 3.5-A resolution. Potassium 54-63 ETS transcription factor ERG Homo sapiens 123-127