PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33325610-9	2021	Co-administration of the ROS inhibitor NAC largely abolished the up-regulated p53 protein level, and rescued the suppressed viability and colony formation ability in butein-exposed U-2 OS cells.	Reactive Oxygen Species	25-28	tumor protein p53	Homo sapiens	78-81	
33325610-10	2021	Taken together, our data proposed the increased ROS by butein exposure activated p53, and the activated p53 was involved in the anti-proliferative effect of butein via inducing senescence in U-2 OS cells.	Reactive Oxygen Species	48-51	tumor protein p53	Homo sapiens	81-84