PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33293849-5 2020 Conversely, low-level local ROS play an important role both as redox-signaling molecules in a wide spectrum of pathways involved in the maintenance of cellular homeostasis (MAPK/ERK, PTK/PTP, PI3K-AKT-mTOR), and regulating key transcription factors (NFkappaB/IkappaB, Nrf2/KEAP1, AP-1, p53, HIF-1). Reactive Oxygen Species 28-31 tumor protein p53 Homo sapiens 286-289