PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33184449-0 2021 Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway. Hydrogen Peroxide 56-73 mitogen-activated protein kinase 8 Mus musculus 86-89 33184449-6 2021 H2O2 incubation activated mitogen-activated protein kinases (MAPKs) pathways, including the extracellular signal-regulated kinase1/2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38 pathways. Hydrogen Peroxide 0-4 mitogen-activated protein kinase 8 Mus musculus 143-166 33184449-6 2021 H2O2 incubation activated mitogen-activated protein kinases (MAPKs) pathways, including the extracellular signal-regulated kinase1/2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38 pathways. Hydrogen Peroxide 0-4 mitogen-activated protein kinase 8 Mus musculus 168-171 33184449-9 2021 Together, our data demonstrate that H2O2 increases ASIC1a expression/activation through the JNK signaling pathway, which may provide insight into the pathogenesis of neurological disorders that involve both ROS and activation of ASIC1a. Hydrogen Peroxide 36-40 mitogen-activated protein kinase 8 Mus musculus 92-95