PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33145420-3	2020	The native substrate of Cp is Fe2+.	ammonium ferrous sulfate	30-34	ceruloplasmin	Homo sapiens	24-26	
33145420-5	2020	In human serum, Cp operates under substrate-limiting low [Fe2+] but high [O2] conditions, implying the possible involvement of partially reduced intermediates in Cp catalysis.	ammonium ferrous sulfate	58-62	ceruloplasmin	Homo sapiens	16-18	
33145420-7	2020	Our results lead to a new hypothesis that human iron transport is regulated as the paired transfer of iron from ferroportin to Cp to transferrin, and the tyrosine residue in Cp acts as a gate to avoid reactive oxygen species (ROS) formation when Fe2+ delivery is dysregulated.	ammonium ferrous sulfate	246-250	ceruloplasmin	Homo sapiens	174-176