PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32371497-0	2020	p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators.	NAD	77-81	tumor protein p53	Homo sapiens	0-3	
32371497-3	2020	Here, using human breast cancer cell models, we identified a pathway in which changes in the extramitochondrial-free NADH:NAD+ ratio signaled through the CtBP family of NADH-sensitive transcriptional regulators to control the abundance and activity of p53.	NAD	117-121	tumor protein p53	Homo sapiens	252-255	
32371497-3	2020	Here, using human breast cancer cell models, we identified a pathway in which changes in the extramitochondrial-free NADH:NAD+ ratio signaled through the CtBP family of NADH-sensitive transcriptional regulators to control the abundance and activity of p53.	NAD	122-126	tumor protein p53	Homo sapiens	252-255	
32371497-3	2020	Here, using human breast cancer cell models, we identified a pathway in which changes in the extramitochondrial-free NADH:NAD+ ratio signaled through the CtBP family of NADH-sensitive transcriptional regulators to control the abundance and activity of p53.	NAD	169-173	tumor protein p53	Homo sapiens	252-255	
32371497-4	2020	NADH-free forms of CtBPs cooperated with the p53-binding partner HDM2 to suppress p53 function, and loss of these forms in highly glycolytic cells resulted in p53 accumulation.	NAD	0-4	tumor protein p53	Homo sapiens	82-85	
32371497-4	2020	NADH-free forms of CtBPs cooperated with the p53-binding partner HDM2 to suppress p53 function, and loss of these forms in highly glycolytic cells resulted in p53 accumulation.	NAD	0-4	tumor protein p53	Homo sapiens	82-85	
32371497-5	2020	We propose that this pathway represents a "glycolytic stress response" in which the initiation of a protective p53 response by an increased NADH:NAD+ ratio enables cells to avoid cellular damage caused by mismatches between metabolic supply and demand.	NAD	140-144	tumor protein p53	Homo sapiens	111-114	
32371497-5	2020	We propose that this pathway represents a "glycolytic stress response" in which the initiation of a protective p53 response by an increased NADH:NAD+ ratio enables cells to avoid cellular damage caused by mismatches between metabolic supply and demand.	NAD	145-149	tumor protein p53	Homo sapiens	111-114