PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32111081-0	2020	Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells.	Reactive Oxygen Species	46-49	tumor protein p53	Homo sapiens	7-10	
32111081-4	2020	Several studies reported that in contrast with the wild type protein, mutant p53 isoforms fail to exert antioxidant activities and rather increase intracellular ROS, driving a pro-tumorigenic survival.	Reactive Oxygen Species	161-164	tumor protein p53	Homo sapiens	77-80	
32111081-5	2020	These pro-oxidant oncogenic abilities of GOF mutant p53 include signaling and metabolic rewiring, as well as the modulation of critical ROS-related transcription factors and antioxidant systems, which lead ROS unbalance linked to tumor progression.	Reactive Oxygen Species	136-139	tumor protein p53	Homo sapiens	52-55	
32111081-5	2020	These pro-oxidant oncogenic abilities of GOF mutant p53 include signaling and metabolic rewiring, as well as the modulation of critical ROS-related transcription factors and antioxidant systems, which lead ROS unbalance linked to tumor progression.	Reactive Oxygen Species	206-209	tumor protein p53	Homo sapiens	52-55	
32111081-6	2020	The studies summarized here highlight that GOF mutant p53 isoforms might constitute major targets for selective therapeutic intervention against several types of tumors and that ROS enhancement driven by mutant p53 might represent an "Achilles heel" of cancer cells, suggesting pro-oxidant drugs as a therapeutic approach for cancer patients bearing the mutant TP53 gene.	Reactive Oxygen Species	178-181	tumor protein p53	Homo sapiens	211-214