PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32012273-0 2020 Cation-chloride cotransporters and the polarity of GABA signalling in mouse hippocampal parvalbumin interneurons. Chlorides 7-15 parvalbumin Mus musculus 88-99 32012273-0 2020 Cation-chloride cotransporters and the polarity of GABA signalling in mouse hippocampal parvalbumin interneurons. gamma-Aminobutyric Acid 51-55 parvalbumin Mus musculus 88-99 32012273-1 2020 KEY POINTS: Cation-chloride cotransporters (CCCs) play a critical role in controlling the efficacy and polarity of GABAA receptor (GABAAR)-mediated transmission in the brain, yet their expression and function in GABAergic interneurons has been overlooked. Chlorides 19-27 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus 115-129 32012273-1 2020 KEY POINTS: Cation-chloride cotransporters (CCCs) play a critical role in controlling the efficacy and polarity of GABAA receptor (GABAAR)-mediated transmission in the brain, yet their expression and function in GABAergic interneurons has been overlooked. Chlorides 19-27 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus 131-137 32012273-7 2020 ABSTRACT: Transmembrane chloride gradients govern the efficacy and polarity of GABA signalling in neurons and are usually maintained by the activity of cation chloride cotransporters, such as KCC2 and NKCC1. Chlorides 24-32 solute carrier family 12, member 5 Mus musculus 192-196 32012273-7 2020 ABSTRACT: Transmembrane chloride gradients govern the efficacy and polarity of GABA signalling in neurons and are usually maintained by the activity of cation chloride cotransporters, such as KCC2 and NKCC1. Chlorides 24-32 solute carrier family 12, member 2 Mus musculus 201-206 32012273-7 2020 ABSTRACT: Transmembrane chloride gradients govern the efficacy and polarity of GABA signalling in neurons and are usually maintained by the activity of cation chloride cotransporters, such as KCC2 and NKCC1. gamma-Aminobutyric Acid 79-83 solute carrier family 12, member 5 Mus musculus 192-196 32012273-7 2020 ABSTRACT: Transmembrane chloride gradients govern the efficacy and polarity of GABA signalling in neurons and are usually maintained by the activity of cation chloride cotransporters, such as KCC2 and NKCC1. gamma-Aminobutyric Acid 79-83 solute carrier family 12, member 2 Mus musculus 201-206 32012273-7 2020 ABSTRACT: Transmembrane chloride gradients govern the efficacy and polarity of GABA signalling in neurons and are usually maintained by the activity of cation chloride cotransporters, such as KCC2 and NKCC1. Chlorides 159-167 solute carrier family 12, member 5 Mus musculus 192-196 32012273-7 2020 ABSTRACT: Transmembrane chloride gradients govern the efficacy and polarity of GABA signalling in neurons and are usually maintained by the activity of cation chloride cotransporters, such as KCC2 and NKCC1. Chlorides 159-167 solute carrier family 12, member 2 Mus musculus 201-206 32012273-11 2020 Focal GABA uncaging in whole-cell recordings reveal that KCC2 and NKCC1 are functional in both PV INs and PCs but differentially contribute to transmembrane chloride gradients in their soma and dendrites. gamma-Aminobutyric Acid 6-10 solute carrier family 12, member 5 Mus musculus 57-61 32012273-11 2020 Focal GABA uncaging in whole-cell recordings reveal that KCC2 and NKCC1 are functional in both PV INs and PCs but differentially contribute to transmembrane chloride gradients in their soma and dendrites. gamma-Aminobutyric Acid 6-10 solute carrier family 12, member 2 Mus musculus 66-71 32012273-11 2020 Focal GABA uncaging in whole-cell recordings reveal that KCC2 and NKCC1 are functional in both PV INs and PCs but differentially contribute to transmembrane chloride gradients in their soma and dendrites. Chlorides 157-165 solute carrier family 12, member 5 Mus musculus 57-61 32012273-11 2020 Focal GABA uncaging in whole-cell recordings reveal that KCC2 and NKCC1 are functional in both PV INs and PCs but differentially contribute to transmembrane chloride gradients in their soma and dendrites. Chlorides 157-165 solute carrier family 12, member 2 Mus musculus 66-71 32012273-15 2020 Altogether our data demonstrate similar mechanisms of chloride regulation in mouse hippocampal PV INs and PCs and suggest KCC2 downregulation in the pathology may affect the valence of GABA signalling in both cell types. gamma-Aminobutyric Acid 185-189 solute carrier family 12, member 5 Mus musculus 122-126