PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31804169-5 2020 It has been observed that nickel exposure induces the generation of reactive oxygen species which leads to the increased expression of p53, NF-kbeta, AP-1, and MAPK. Oxygen 77-83 tumor protein p53 Homo sapiens 135-138