PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31753397-9 2020 Furthermore, we found that SIRT1 inhibition by nicotinamide completely counteracted the protective effect of DECM on chondrocytes in the presence of IL-1beta or TNF-alpha, indicating that the SIRT1 signaling pathway was involved in the DECM-mediated enhancement of anti-inflammatory properties of chondrocytes. Niacinamide 47-59 tumor necrosis factor Homo sapiens 161-170