PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31621310-7 2019 These results coupled with simulation studies modeling flavonoid interaction within the AhR binding pocket demonstrate that the orientation of the substituted phenyl ring at C-2 (flavones) or C-3 (isoflavones) on the common 4-H-chromen-4-one ring strongly influences the activities of isoflavones and flavones as AhR agonists. Isoflavones 197-208 complement C3 Homo sapiens 192-195 31621310-7 2019 These results coupled with simulation studies modeling flavonoid interaction within the AhR binding pocket demonstrate that the orientation of the substituted phenyl ring at C-2 (flavones) or C-3 (isoflavones) on the common 4-H-chromen-4-one ring strongly influences the activities of isoflavones and flavones as AhR agonists. Isoflavones 285-296 complement C3 Homo sapiens 192-195