PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31506575-7 2019 Moreover, downregulation of JNK by its specific inhibitor SP600125 significantly diminished the anticancer activity of APE indicating that ROS generation and sustained JNK activation represented the main underlying mechanism of APE-induced cell death. Reactive Oxygen Species 139-142 mitogen-activated protein kinase 8 Homo sapiens 28-31