PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31202736-5 2019 In this study, we showed that treatment with the indirect CAR activator phenobarbital activated transcription of the CYP3A4 gene in three-dimensionally (3D)-cultured HepG2 cells. Phenobarbital 72-85 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 117-123 31202736-7 2019 Moreover, okadaic acid and epidermal growth factor, were found to repress phenobarbital-induced CAR nuclear translocation and subsequent activation of the CYP3A4 gene promoter. Phenobarbital 74-87 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 155-161