PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30555323-11 2018 In LPS-primed THP-1 cells stimulated by nigericin (a model to study the NLRP3 inflammasome), rifaximin reduced IL-1beta production in a concentration-dependent fashion, this effect being associated with inhibition of the up-stream caspase-1 activation. Nigericin 40-49 NLR family pyrin domain containing 3 Homo sapiens 72-77