PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30451372-3	2019	Urokinase + tranexamic acid produces plasmin in plasma or blood and disrupts clotting.	Tranexamic Acid	12-27	plasminogen	Homo sapiens	37-44	
30451372-10	2019	Results IC50 values for antifibrinolytic activity of TXA varied from < 10 to > 1000 mumol L-1 depending on the system, but good fibrin protection was observed in the presence of tPA, uPA and plasmin.	Tranexamic Acid	53-56	plasminogen	Homo sapiens	191-198	
30451372-11	2019	However, in plasma or blood, active plasmin was generated by TXA + uPA (but not tPA) and coagulopathy developed leading to no or poor clot formation.	Tranexamic Acid	61-64	plasminogen	Homo sapiens	36-43	
30451372-16	2019	Conclusions Tranexamic acid protects fibrin but stimulates uPA activity and slows inhibition of plasmin by alpha2 -antiplasmin.	Tranexamic Acid	12-27	plasminogen	Homo sapiens	96-103	
30451372-18	2019	Additional direct inhibition of plasmin by aprotinin may prevent development of coagulopathy and extend the useful time window of TXA treatment.	Tranexamic Acid	130-133	plasminogen	Homo sapiens	32-39