PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30384258-1 2019 We recently reported that siRNA-knockdown of delta-5-desaturase (D5D), the rate-limiting enzyme converting upstream omega - 6 dihomo-gamma-linolenic acid (DGLA) to arachidonic acid, promoted formation of the anti-cancer byproduct 8-hydroxyoctanoic acid (8-HOA) from COX-2-catalyzed DGLA peroxidation, consequently suppressing pancreatic cancer cell growth, migration and invasion. Arachidonic Acid 164-180 mitochondrially encoded cytochrome c oxidase II Homo sapiens 266-271