PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30279516-0 2019 NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions. Reactive Oxygen Species 13-16 NADPH oxidase 1 Homo sapiens 0-4 30279516-0 2019 NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions. Reactive Oxygen Species 13-16 lipocalin 2 Homo sapiens 41-52 30279516-2 2019 The major source of ROS in intestinal epithelial cells is the NADPH oxidase NOX1, which consists of the transmembrane proteins, NOX1 and p22PHOX, and the cytosolic proteins, NOXO1, NOXA1, and Rac1. Reactive Oxygen Species 20-23 NADPH oxidase 1 Homo sapiens 76-80 30279516-2 2019 The major source of ROS in intestinal epithelial cells is the NADPH oxidase NOX1, which consists of the transmembrane proteins, NOX1 and p22PHOX, and the cytosolic proteins, NOXO1, NOXA1, and Rac1. Reactive Oxygen Species 20-23 NADPH oxidase 1 Homo sapiens 128-132 30279516-2 2019 The major source of ROS in intestinal epithelial cells is the NADPH oxidase NOX1, which consists of the transmembrane proteins, NOX1 and p22PHOX, and the cytosolic proteins, NOXO1, NOXA1, and Rac1. Reactive Oxygen Species 20-23 cytochrome b-245 alpha chain Homo sapiens 137-144 30279516-2 2019 The major source of ROS in intestinal epithelial cells is the NADPH oxidase NOX1, which consists of the transmembrane proteins, NOX1 and p22PHOX, and the cytosolic proteins, NOXO1, NOXA1, and Rac1. Reactive Oxygen Species 20-23 NADPH oxidase organizer 1 Homo sapiens 174-179 30279516-2 2019 The major source of ROS in intestinal epithelial cells is the NADPH oxidase NOX1, which consists of the transmembrane proteins, NOX1 and p22PHOX, and the cytosolic proteins, NOXO1, NOXA1, and Rac1. Reactive Oxygen Species 20-23 NADPH oxidase activator 1 Homo sapiens 181-186 30279516-2 2019 The major source of ROS in intestinal epithelial cells is the NADPH oxidase NOX1, which consists of the transmembrane proteins, NOX1 and p22PHOX, and the cytosolic proteins, NOXO1, NOXA1, and Rac1. Reactive Oxygen Species 20-23 Rac family small GTPase 1 Homo sapiens 192-196 30279516-4 2019 We found that the combination of TNFalpha and IL-17 induced a dramatic upregulation of NOXO1 expression that was dependent on the activation of p38MAPK and JNK1/2, and resulted into an increase of NOX1 activity and ROS production. Reactive Oxygen Species 215-218 tumor necrosis factor Homo sapiens 33-41 30279516-4 2019 We found that the combination of TNFalpha and IL-17 induced a dramatic upregulation of NOXO1 expression that was dependent on the activation of p38MAPK and JNK1/2, and resulted into an increase of NOX1 activity and ROS production. Reactive Oxygen Species 215-218 interleukin 17A Homo sapiens 46-51 30279516-4 2019 We found that the combination of TNFalpha and IL-17 induced a dramatic upregulation of NOXO1 expression that was dependent on the activation of p38MAPK and JNK1/2, and resulted into an increase of NOX1 activity and ROS production. Reactive Oxygen Species 215-218 NADPH oxidase organizer 1 Homo sapiens 87-92 30279516-5 2019 NOX1-derived ROS drive the expression of LCN-2 by controlling the expression of IkappaBzeta, a master inducer of LCN-2. Reactive Oxygen Species 13-16 NADPH oxidase 1 Homo sapiens 0-4 30279516-5 2019 NOX1-derived ROS drive the expression of LCN-2 by controlling the expression of IkappaBzeta, a master inducer of LCN-2. Reactive Oxygen Species 13-16 lipocalin 2 Homo sapiens 41-46 30279516-5 2019 NOX1-derived ROS drive the expression of LCN-2 by controlling the expression of IkappaBzeta, a master inducer of LCN-2. Reactive Oxygen Species 13-16 NFKB inhibitor zeta Homo sapiens 80-91 30279516-5 2019 NOX1-derived ROS drive the expression of LCN-2 by controlling the expression of IkappaBzeta, a master inducer of LCN-2. Reactive Oxygen Species 13-16 lipocalin 2 Homo sapiens 113-118