PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3023367-2 1986 In platelets activated by thrombin, the hydrolysis of phosphatidylinositol 4,5-bisphosphate by phospholipase C produces inositol 1,4,5-triphosphate (IP3) and diacylglycerol, metabolites which are known to cause Ca2+ release from the platelet dense tubular system and granule secretion. Phosphatidylinositol 4,5-Diphosphate 54-91 coagulation factor II, thrombin Homo sapiens 26-34