PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30216848-5 2018 Furthermore, in vitro COX-1/COX-2 inhibition testing showed that the compounds 4b, 6c, 10b, and 10c exhibited effective COX-2 inhibition, with IC50 values of 0.40-1.20 muM, and selectivity index (SI) values of >62.50-20.83, using celecoxib as a reference drug (IC50 = 0.11 muM; COX-2 SI: >227.20). Celecoxib 233-242 mitochondrially encoded cytochrome c oxidase II Homo sapiens 120-125 30216848-5 2018 Furthermore, in vitro COX-1/COX-2 inhibition testing showed that the compounds 4b, 6c, 10b, and 10c exhibited effective COX-2 inhibition, with IC50 values of 0.40-1.20 muM, and selectivity index (SI) values of >62.50-20.83, using celecoxib as a reference drug (IC50 = 0.11 muM; COX-2 SI: >227.20). Celecoxib 233-242 mitochondrially encoded cytochrome c oxidase II Homo sapiens 120-125